Structure and function of the UV-B photoreceptor UVR8

•Brief overview of the structure and function of UVR8.•Summary of recent research on the mechanism of UVR8 photoreception.•Review of interactions of UVR8 with proteins involved in signalling and regulation. UVR8 is a UV-B photoreceptor that employs specific tryptophans in its primary sequence as chr...

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Bibliographic Details
Published inCurrent opinion in structural biology Vol. 29; pp. 52 - 57
Main Author Jenkins, Gareth I
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.12.2014
Subjects
Arabidopsis - chemistry
Arabidopsis Proteins - chemistry
Chromosomal Proteins, Non-Histone - chemistry
Models, Molecular
Photoreceptors, Plant - chemistry
Protein Conformation
Protein Multimerization
Signal Transduction
Ubiquitin-Protein Ligases - chemistry
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Summary:•Brief overview of the structure and function of UVR8.•Summary of recent research on the mechanism of UVR8 photoreception.•Review of interactions of UVR8 with proteins involved in signalling and regulation. UVR8 is a UV-B photoreceptor that employs specific tryptophans in its primary sequence as chromophores in photoreception. UV-B absorption causes dissociation of the dimeric photoreceptor by neutralizing interactions between monomers. The monomeric form initiates signalling through interaction with the COP1 protein, leading to transcriptional responses. This article discusses the structural basis of UVR8 function, highlighting recent research on the mechanism of photoreception and on interactions with other proteins involved in signalling and regulation.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0959-440X
1879-033X
DOI:10.1016/j.sbi.2014.09.004