Effect of yoga intervention on biochemical, oxidative stress markers, inflammatory markers and sleep quality among subjects with type 2 diabetes in South India: Results from the SATYAM project

• Published in: Diabetes research and clinical practice Vol. 172; p. 108644
• Main Authors: Viswanathan, Vijay, Sivakumar, Sumathi, Sai Prathiba, A., Devarajan, Arutselvi, George, Leema, Kumpatla, Satyavani
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.02.2021
• Subjects: Biochemical; Biomarkers; Diabetes Mellitus, Type 2 - blood; Female; Humans; India; Inflammation - therapy; Inflammatory markers; Male; Middle Aged; Oxidative stress; Oxidative Stress - physiology; Sleep quality; Sleep Wake Disorders - etiology; Type 2 diabetes & Yoga; Yoga - psychology; India; Oxidative stress; Sleep quality; Type 2 diabetes & Yoga; Biochemical; Inflammatory markers
• ISSN: 0168-8227; 1872-8227; 1872-8227
• DOI: 10.1016/j.diabres.2020.108644

The aim of this study was to investigate the effect of yoga intervention on the biochemical, oxidative stress markers and inflammatory markers and sleep quality among subjects with type 2 diabetes. Subjects with type 2 diabetes attending a tertiary care centre for diabetes during Feb 2017 to Oct 2019 in Chennai, India were randomly assigned to two different groups. Group1(non-Yoga) (n = 150) was advised on simple physical exercises whereas group2(Yoga) (n = 150) was trained and advised to do yogasanas with static loosening exercises for 50 min for 5 days in a week. Both the groups were followed up for a period of 3 months. Anthropometric, biochemical, oxidative stress markers, inflammatory markers and sleep quality were assessed at baseline and after follow up. There was a significant reduction in BMI, blood glucose levels, HbA1c, lipid levels, IL6, TNFα and TBARS in Yoga group as compared to non-Yoga group. There was marked improvement in the levels of Adiponectin, PTGIS and sleep quality among subjects practising yogasanas. Regular practice of yogasanas improved glycaemic control, oxidative stress, inflammatory response and sleep quality among subjects with type 2 diabetes. Hence, Yogasanas can be used as an adjuvant therapy for managing type 2 diabetes.