Lipid-coated nanocapillaries for DNA sensing

We report a simple and efficient way to accomplish the chemical modification of glass nanopores by means of lipid self-assembly. Lipid coating improves the success rate of these glass nanopores as biosensors to detect λ-DNA.

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Bibliographic Details
Published inAnalyst (London) Vol. 138; no. 1; pp. 104 - 106
Main Authors Hernández-Ainsa, Silvia, Muus, Christoph, Bell, Nicholas A W, Steinbock, Lorenz J, Thacker, Vivek V, Keyser, Ulrich F
Format Journal Article
LanguageEnglish
Published England 01.01.2013
Subjects
Bacteriophage lambda
Biosensing Techniques - methods
Biosensors
Deoxyribonucleic acid
Detection
DNA, Viral - analysis
Glass
Glass - chemistry
Lipids
Nanopores
Nanostructure
Phosphatidylcholines - chemistry
Porosity
Self assembly
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Summary:We report a simple and efficient way to accomplish the chemical modification of glass nanopores by means of lipid self-assembly. Lipid coating improves the success rate of these glass nanopores as biosensors to detect λ-DNA.
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ISSN:0003-2654
1364-5528
DOI:10.1039/c2an36397f