Paper based colorimetric detection of miRNA-21 using Ag/Pt nanoclusters

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 227; p. 117529
• Main Authors: Fakhri, Neda, Abarghoei, Shima, Dadmehr, Mehdi, Hosseini, Morteza, Sabahi, Hossein, Ganjali, Mohammad Reza
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.02.2020
• Subjects: Cancer; Colorimetric; DNA-Ag/Pt nanoclusters; Paper based; Peroxidase; Paper based; Peroxidase; DNA-Ag/Pt nanoclusters; Colorimetric; Cancer

Abnormal expression of MicroRNA-21 (miRNA-21) is considered to be a reliable biomarker for the early diagnosis of cancer. In this work, a novel paper based biosensor was fabricated to detect sub-micro molar concentrations of miRNA-21 based on peroxidase mimetic activity of DNA-templated Ag/Pt nanocl...