Giardiasis among different tribes of Orang Asli in Malaysia: Highlighting the presence of other family members infected with Giardia intestinalis as a main risk factor

• Published in: International journal for parasitology Vol. 42; no. 9; pp. 871 - 880
• Main Authors: Anuar, Tengku Shahrul, Al-Mekhlafi, Hesham M., Ghani, Mohamed Kamel Abdul, Osman, Emelia, Yasin, Azlin Mohd, Nordin, Anisah, Azreen, Siti Nor, Salleh, Fatmah Md, Ghazali, Nuraffini, Bernadus, Mekadina, Moktar, Norhayati
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2012
• Subjects: Adolescent; Adult; Age; Aged; Animals; case studies; children; community health; cross-sectional studies; Data processing; Developing countries; Diarrhea; Family; Feces; Feces - parasitology; Female; females; Flagellates; Food; food sanitation; Giardia intestinalis; Giardia lamblia; Giardia lamblia - isolation & purification; Giardiasis; Giardiasis - epidemiology; health education; Humans; Hygiene; Infection; Inventories; logit analysis; Malaysia; Malaysia - epidemiology; Male; males; Middle Aged; Orang Asli tribes; parasites; people; Population studies; Prevalence; Public health; questionnaires; raw vegetables; Regression analysis; Risk Factors; Sedimentation; Socio-economic aspects; subtropics; tropics; Vegetables; Young Adult; Malaysia; Orang Asli tribes; Malaysia; Giardiasis; Giardia intestinalis; Risk factors
• ISSN: 0020-7519; 1879-0135
• DOI: 10.1016/j.ijpara.2012.07.003

[Display omitted] ► The Proto-Malay area showed a higher prevalence of giardiasis than Negrito and Senoi areas with lower sanitary conditions. ► Infected individuals in the same household can serve as a source of Giardia intestinalis. ► Persons less than 24years of age have the highest prevalence of giardiasis. ► Identifying and treating the carriers within the family as the main strategy in the control of giardiasis among Orang Asli. The flagellate protozoan parasite, Giardia intestinalis, is widely distributed throughout the world with a high prevalence in developing countries in the tropics and subtropics, including Malaysia. Approximately 200 million people are infected with the parasite globally, with 500,000 new cases reported annually. This cross-sectional study was conducted among three tribes of Orang Asli communities in Selangor, Perak and Pahang states of Malaysia. The main objective was to determine the prevalence of and risk factors for giardiasis. Stool samples were collected from 500 individuals aged between 2 and 74years (males=219, females=281). The samples were examined with formalin–ether sedimentation and trichrome staining techniques. Socioeconomic data were collected through a pre-tested questionnaire. The overall prevalence of giardiasis was 20.0% with the highest prevalence in the Proto-Malays (33.3%) followed by Negritos (20.1%) and Senois (10.4%). The positive cases showed a decrease with increasing age and most of the positive cases were observed in individuals less than 24years old. Males had significantly higher prevalence than females (χ2=5.283, P=0.022). Logistic regression analysis of the overall population studied and the Senoi tribe confirmed that being a child aged less than 15years, being male, the consumption of raw vegetables and the presence of other family members infected with G. intestinalis were the main risk factors for giardiasis. The presence of other family members infected with G. intestinalis was the only risk factor highlighted in the Proto-Malay and Negrito tribes. Diarrhoea was significantly associated with giardiasis. However, the cause and effect relationship has yet to be determined. Thus, screening family members and treating the infected individuals are the main strategies that should be adopted by the public health authority in combating this infection in Orang Asli communities as well as health education regarding good personal and food hygiene practises.