Potassium hydrogen sulfate-catalyzed reactions of indoles: A mild, expedient synthesis of bis-indolylmethanes

Biologically important bis-indolylmethanes and their derivatives were prepared in good yields by the electrophilic substitution of indole with aldehydes catalyzed by potassium hydrogen sulfate.

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Bibliographic Details
Published inChemistry letters Vol. 33; no. 3; pp. 288 - 289
Main Authors Nagarajan, R, Perumal, PT
Format Journal Article
LanguageEnglish
Published TOKYO Chemical Soc Japan 01.03.2004
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
STREPTINDOLE
VIBRINDOLE-A
ACID
NITRONES
BIS(INDOLYL)METHANES
DIINDOLYLALKANES
CARBONYL-COMPOUNDS
ALDEHYDES
METABOLITE
CLAY
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Summary:Biologically important bis-indolylmethanes and their derivatives were prepared in good yields by the electrophilic substitution of indole with aldehydes catalyzed by potassium hydrogen sulfate.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2004.288