Therapeutic applications of carbon nanotubes: opportunities and challenges

Based on their physicochemical properties that allow efficient functionalization with biomolecules and cellular membrane translocation, as well as on their applications in Raman and near-infrared fluorescence imaging, carbon nanotubes (CNTs) have been proposed as viable candidates for developing the...

Full description

Saved in:
Bibliographic Details
Published inWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology Vol. 6; no. 4; p. 327
Main Authors Rogers-Nieman, Gabrielle M, Dinu, Cerasela Zoica
Format Journal Article
LanguageEnglish
Published United States 01.07.2014
Subjects
Humans
Nanostructures - therapeutic use
Nanotechnology - trends
Nanotubes, Carbon
Neoplasms - therapy
Online AccessGet more information

Cover

More Information
Summary:Based on their physicochemical properties that allow efficient functionalization with biomolecules and cellular membrane translocation, as well as on their applications in Raman and near-infrared fluorescence imaging, carbon nanotubes (CNTs) have been proposed as viable candidates for developing therapeutic platforms that ensure targeting of tumor cells without affecting healthy cells. This article reviews the research on toxicological effects of CNTs on host cells, as well as their pharmacological profiles on cancer cells. The potential impact of this approach is discussed along with some potential pitfalls that will need to be overcome when therapeutic implementation CNTs are considered. For further resources related to this article, please visit the WIREs website. The authors declare no competing financial interest.
ISSN:1939-0041
DOI:10.1002/wnan.1268