Anti-Holley (hy): characterization of another example

Anti-Hy, in a serum of a black man who had received multiple blood transfusions, was found to be a warm reactive and polyclonal IgG antibody which did not bind complement in vitro. 51Cr-labeled Hy-positive red blood cells in the patient showed a shortened "2-component" survival curve. Hy a...

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Bibliographic Details
Published inTransfusion (Philadelphia, Pa.) Vol. 15; no. 6; p. 604
Main Authors Hsu, T C, Jagathambal, K, Sabo, B H, Sawitsky, A
Format Journal Article
LanguageEnglish
Published United States 01.11.1975
Subjects
Adsorption
Adult
Blood Group Antigens
Complement Fixation Tests
Coombs Test
Cytotoxicity Tests, Immunologic
Erythrocyte Aging
Hemagglutination Inhibition Tests
Humans
Immunoglobulin G - analysis
Isoantibodies - analysis
Male
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Summary:Anti-Hy, in a serum of a black man who had received multiple blood transfusions, was found to be a warm reactive and polyclonal IgG antibody which did not bind complement in vitro. 51Cr-labeled Hy-positive red blood cells in the patient showed a shortened "2-component" survival curve. Hy antigens were not detected on leukocytes, platelets, or in the serum of Hy-positive individuals.
ISSN:0041-1132
DOI:10.1046/j.1537-2995.1975.15676082238.x