Interplay between miRNAs and human diseases

• Published in: Journal of cellular physiology Vol. 233; no. 3; pp. 2007 - 2018
• Main Authors: Paul, Prosenjit, Chakraborty, Anindya, Sarkar, Debasree, Langthasa, Malobika, Rahman, Musfhia, Bari, Minakshi, Singha, RK. Sanamacha, Malakar, Arup Kumar, Chakraborty, Supriyo
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2018
• Subjects: Atherosclerosis - genetics; Cancer; Cardiomyopathies - genetics; Cardiovascular diseases; Diabetes mellitus; Diabetes Mellitus - genetics; Gene Regulatory Networks; Homeostasis; Humans; insulin; kidney disease; Kidney diseases; Kidney Diseases - genetics; Kidney transplantation; MicroRNAs; MicroRNAs - genetics; miRNA; Neoplasms - genetics; homeostasis; kidney disease; miRNA; cancer; insulin
• ISSN: 0021-9541; 1097-4652; 1097-4652
• DOI: 10.1002/jcp.25854

MicroRNAs (miRNAs) are endogenous, non‐coding RNAs, which have evoked a great deal of interest due to their importance in many aspects of homeostasis and diseases. MicroRNAs are stable and are essential components of gene regulatory networks. They play a crucial role in healthy individuals and their dysregulations have also been implicated in a wide range of diseases, including diabetes, cardiovascular disease, kidney disease, and cancer. This review summarized the current understanding of interactions between miRNAs and different diseases and their role in disease diagnosis and therapy. This review summarized the current understanding of interactions between miRNAs and different diseases and their role in disease diagnosis and therapy.