Malignant nerve sheath tumors of the head and neck: a combined experience from two university hospitals

Malignant schwannoma is an aggressive neoplasm whose cell of origin and histologic characteristics remain controversial. Despite advances in diagnostic techniques, the natural history of this tumor remains uncertain. The charts of all patients with malignant schwannoma who were treated at the UCLA C...

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Bibliographic Details
Published inThe Laryngoscope Vol. 101; no. 10; p. 1044
Main Authors Bailet, J W, Abemayor, E, Andrews, J C, Rowland, J P, Fu, Y S, Dawson, D E
Format Journal Article
LanguageEnglish
Published United States 01.10.1991
Subjects
Adolescent
Adult
Aged
Combined Modality Therapy
Female
Head and Neck Neoplasms - diagnosis
Head and Neck Neoplasms - mortality
Head and Neck Neoplasms - therapy
Hospitals, University
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neurilemmoma - diagnosis
Neurilemmoma - mortality
Neurilemmoma - therapy
Prognosis
Retrospective Studies
Survival Rate
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Summary:Malignant schwannoma is an aggressive neoplasm whose cell of origin and histologic characteristics remain controversial. Despite advances in diagnostic techniques, the natural history of this tumor remains uncertain. The charts of all patients with malignant schwannoma who were treated at the UCLA Center for the Health Sciences and the University of Iowa Hospital and Clinics were retrospectively reviewed. Sixteen patients received surgery and radiotherapy in combination or as sole therapy. Irrespective of treatment modality, prognosis was poor with an overall survival of 15%. Recent advances in imaging and histologic techniques that assist in establishing the diagnosis and delineating tumor location are discussed. In addition, the literature pertaining to malignant schwannoma of the head and neck is reviewed.
ISSN:0023-852X
1531-4995
DOI:10.1288/00005537-199110000-00003