Differentiation of Junin Virus and Antigenic Variants Isolated in vivo by Kinetic Neutralization Assays

• Published in: Journal of general virology Vol. 69; no. 8; pp. 2123 - 2127
• Main Authors: Alche, Laura E, Coto, Celia E
• Format: Journal Article
• Language: English
• Published: Reading Soc General Microbiol 01.08.1988; Society for General Microbiology
• Subjects: Animals; Antibodies, Viral - immunology; Antigenic Variation; Antigens, Viral - analysis; Arenaviridae - isolation & purification; Arenaviruses, New World - immunology; Arenaviruses, New World - isolation & purification; Arvicolinae; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Hemorrhagic Fever, American - microbiology; Junin virus; Kinetics; Microbiology; Neutralization Tests; Techniques used in virology; Virology; Antibody; Rodentia; Kinetic method; Junin virus; Immunological method; Virus; Variant; Vertebrata; Mammalia; Neutralization test; Mouse; Newborn animal; Antigenic variation; Arenaviridae

Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón II, Piso 4, 1428-Buenos Aires, Argentina The major natural reservoir of Junin virus, the aetiological agent of Argentine haemorrhagic fever, is the cricetid Ca...