Studies using concentric ring bifocal and peripheral add multifocal contact lenses to slow myopia progression in school‐aged children: a meta‐analysis

• Published in: Ophthalmic & physiological optics Vol. 37; no. 1; pp. 51 - 59
• Main Authors: Li, Shi‐Ming, Kang, Meng‐Tian, Wu, Shan‐Shan, Meng, Bo, Sun, Yun‐Yun, Wei, Shi‐Fei, Liu, Luoru, Peng, Xiaoxia, Chen, Zhuo, Zhang, Fengju, Wang, Ningli
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2017
• Subjects: Child; Children; Contact Lenses; Disease Progression; Elongation; Equipment Design; Humans; Manufacturing; Meta-analysis; Myopia; Myopia, Degenerative - physiopathology; Myopia, Degenerative - therapy; Quality control; Refraction, Ocular - physiology; soft contact lens; Visual Acuity; meta-analysis; myopia; children; soft contact lens
• ISSN: 0275-5408; 1475-1313
• DOI: 10.1111/opo.12332

Purpose To evaluate the effect of soft contact lens with concentric ring bifocal and peripheral add multifocal designs on controlling myopia progression in school‐aged children. Methods We systematically searched MEDLINE, EMBASE, Cochrane Library and reference lists of included trials. Methodological quality of included trials was assessed using Jadad Scale and Newcastle‐Ottawa Quality Assessment Scale items. Results We identified five randomised controlled trials (RCTs) and three cohort studies with a total of 587 myopic children. Compared with the control group, concentric ring bifocal soft contact lenses showed less myopia progression with a weighted mean difference (WMD) of 0.31 D (95% CI, 0.05~0.57 D, p = 0.02) and less axial elongation with a WMD of −0.12 mm (95% CI, approximately −0.18 to −0.07 mm, p < 0.0001) at 12 months. Relative to the control group, peripheral add multifocal soft contact lenses showed less myopia progression with a WMD of 0.22 D (95% CI 0.14~0.31 D, p < 0.0001) and less axial elongation of −0.10 mm (95% CI −0.13~0.07 mm, p < 0.0001) at 12 months, respectively. The soft contact lenses with concentric ring bifocal and peripheral add multifocal designs produced additional myopia control rates of 30~38% for slowing myopia progression and 31~51% for lessening axial elongation within 24 months. Conclusions Both concentric ring bifocal and peripheral add multifocal soft contact lenses are clinically effective for controlling myopia in school‐aged children, with an overall myopia control rates of 30~50% over 2 years. Concentric ring bifocal soft contact lenses seem to have greater effect than peripheral add multifocal soft contact lenses.