Update regarding xenotransplantation in Japan

To overcome the donor shortage, a promising solution could be xenotransplantation. The pig is generally considered the most suitable donor species for xenotransplantation. A clinical xenotransplantation has not been conducted in Japan. However, many progresses have recently been made in this field....

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Bibliographic Details
Published inXenotransplantation (Københaven) Vol. 26; no. 1; pp. e12491 - n/a
Main Authors Shimoda, Masayuki, Matsumoto, Shinichi
Format Journal Article
LanguageEnglish
Published Denmark Wiley Subscription Services, Inc 01.01.2019
Subjects
R&D
Research & development
Xenografts
Xenotransplantation
Zoonoses
Japan
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Summary:To overcome the donor shortage, a promising solution could be xenotransplantation. The pig is generally considered the most suitable donor species for xenotransplantation. A clinical xenotransplantation has not been conducted in Japan. However, many progresses have recently been made in this field. Japan has regulations for conducting cell xenotransplantation and guidelines to prevent zoonosis. Most Japanese patients and their family members have a positive opinion about islet xenotransplantation. A grant for clinical islet xenotransplantation research and development has been approved, and germ‐free pigs have been developed. Further research may bring the successful application of xenotransplantation closer to reality.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0908-665X
1399-3089
DOI:10.1111/xen.12491