Significance and applications of carbon dots in anti cancerous nanodrug conjugate development: A review

• Published in: Applied surface science advances Vol. 19; p. 100550
• Main Authors: Pandey, Vinay Kumar, Tripathi, Anjali, Taufeeq, Anam, Dar, Aamir Hussain, Samrot, Antony V, Rustagi, Sarvesh, Malik, Sumira, Bhattacharya, Tanima, Kovacs, Bela, Shaikh, Ayaz Mukkaram
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.02.2024; Elsevier
• Subjects: Carbon dots; Drug delivery; Nano drug conjugate: anticancer; Nano drug conjugate: anticancer; Drug delivery; Carbon dots
• ISSN: 2666-5239; 2666-5239
• DOI: 10.1016/j.apsadv.2023.100550

Carbon-based nanoparticles known as Carbon Dots (CDs) have attracted a lot of interest in the field of cancer therapy because of their special physicochemical characteristics and biocompatibility. They are attractive carriers for drug delivery systems due to their surface functional ability, superior water solubility, and size-dependent fluorescence. CDs are unique in that they have a large surface area, adjustable surface chemistry, and a remarkable ability to carry anticancer medications. Their lower systemic toxicity, regulated drug release, and capacity to get beyond biological barriers have completely changed the way that drugs are delivered. CDs have a variety of uses in the creation of anti-tumor nanodrug conjugates. CDs have been used in combination therapy, a multimodal strategy for cancer treatment that involves co-delivering various medications for synergistic benefits. The incorporation of CDs into anticancerous has-drug conjugates represents a noteworthy progression in the treatment of cancer medication delivery systems have been revolutionized by their capacity to improve medication stability, target specificity, and controlled release, which holds the promise of more effective and customized treatments. This review article deals with the synthesis of carbon dot-mediated nanodrug conjugate and their roles in cancer therapy.