Changes in Metabolic Syndrome Severity Following Individualized Versus Standardized Exercise Prescription: A Feasibility Study

• Published in: International journal of environmental research and public health Vol. 15; no. 11; p. 2594
• Main Authors: Weatherwax, Ryan M, Ramos, Joyce S, Harris, Nigel K, Kilding, Andrew E, Dalleck, Lance C
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 20.11.2018; MDPI
• Subjects: Blood pressure; Exercise intensity; Feasibility studies; Food; Heart rate; Intervention; Laboratories; Metabolic disorders; Metabolic syndrome; Physical fitness; Questionnaires; Risk analysis; Risk factors; United States > US; ventilatory threshold; HRR; MetS z-score; training responsiveness; exercise non-responders; personalized medicine
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph15112594

This study sought to investigate the efficacy of standardized versus individualized exercise intensity prescription on metabolic syndrome (MetS) severity following a 12-week exercise intervention. A total of 38 experimental participants (47.8 ± 12.2 yr, 170.7 ± 8.0 cm, 82.6 ± 18.7 kg, 26.9 ± 6.7 mL·k ·min ) were randomized to one of two exercise interventions (exercise intensity prescribed using heart rate reserve or ventilatory threshold). Following the 12-week intervention, MetS z-score was significantly improved for the standardized (-2.0 ± 3.1 to -2.8 ± 2.8 [ = 0.01]) and individualized (-3.3 ± 2.3 to -3.9 ± 2.2 [ = 0.04]) groups. When separating participants based on prevalence of MetS at baseline and MetS -score responsiveness, there were six and three participants in the standardized and individualized groups, respectively, with three or more MetS risk factors. Of the six participants in the standardized group, 83% (5/6) of the participants were considered responders, whereas 100% (3/3) of the individualized participants were responders. Furthermore, only 17% (1/6) of the participants with MetS at baseline in the standardized group no longer had symptoms of MetS following the intervention. In the individualized group, 67% (2/3) of participants with baseline MetS were not considered to have MetS at week 12. These findings suggest that an individualized approach to the exercise intensity prescription may ameliorate the severity of MetS.