Relation of C-reactive protein correlates with risk of thromboembolism in patients with atrial fibrillation

• Published in: The American journal of cardiology Vol. 94; no. 6; pp. 805 - 807
• Main Authors: Thambidorai, Senthil K., Parakh, Kapil, Martin, David O., Shah, Tushar K., Wazni, Oussama, Jasper, Susan E., Van Wagoner, David R., Chung, Mina K., Murray, R.Daniel, Klein, Allan L.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.09.2004; Elsevier; Elsevier Limited
• Subjects: Adult; Aged; Analysis of Variance; Atrial Fibrillation - blood; Atrial Fibrillation - complications; Biological and medical sciences; Biomarkers - blood; Blood and lymphatic vessels; C-Reactive Protein - metabolism; Cardiac arrhythmia; Cardiac dysrhythmias; Cardiology; Cardiology. Vascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Echocardiography, Transesophageal; Female; Health risk assessment; Heart; Humans; Male; Medical sciences; Middle Aged; Proteins; Risk Factors; ROC Curve; Statistics, Nonparametric; Thromboembolism - blood; Thromboembolism - diagnostic imaging; Thromboembolism - etiology; Human; Arrhythmia; Atrial fibrillation; Cardiovascular disease; Risk; Thrombosis; Excitability disorder; Embolism; Vascular disease; Heart disease; Risk factor; C reactive protein; Thromboembolism
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2004.06.011

The relation between C-reactive protein, an inflammatory marker, and thromboembolic risk factors was investigated in 104 patients with atrial fibrillation and found that patients with transesophageal echocardiography identified thromboembolic risk factors had greater C-reactive protein levels than those without (1.00 vs 0.302 mg/dl). C-reactive protein also correlated with clinical stroke risk factors. Increased C-reactive protein levels were also independently associated with transesophageal echocardiographic thromboembolic risk factors.