Short-Term Exposure to Fine Particulate Matter and Hospitalizations for Acute Lower Respiratory Infection in Korean Children: A Time-Series Study in Seven Metropolitan Cities
Although several studies have evaluated the association between fine particulate matter (PM ) and acute lower respiratory infection (ALRI) in children, their results were inconsistent Therefore, we aimed to evaluate the association between short-term exposure to PM and ALRI hospitalizations in child...
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Published in | International journal of environmental research and public health Vol. 18; no. 1; p. 144 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
MDPI AG
28.12.2020
MDPI |
Subjects | |
Online Access | Get full text |
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Summary: | Although several studies have evaluated the association between fine particulate matter (PM
) and acute lower respiratory infection (ALRI) in children, their results were inconsistent Therefore, we aimed to evaluate the association between short-term exposure to PM
and ALRI hospitalizations in children (0-5 years) living in seven metropolitan cities of Korea. The ALRI hospitalization data of children living in seven metropolitan cities of Korea from 2008 to 2016 was acquired from a customized database constructed based on National Health Insurance data. The time-series data in a generalized additive model were used to evaluate the relationship between ALRI hospitalization and 7-day moving average PM
exposure after adjusting for apparent temperature, day of the week, and time trends. We performed a meta-analysis using a two-stage design method. The estimates for each city were pooled to generate an average estimate of the associations. The average PM
concentration in 7 metropolitan cities was 29.0 μg/m
and a total of 713,588 ALRI hospitalizations were observed during the 9-year study period. A strong linear association was observed between PM
and ALRI hospitalization. A 10 μg/m
increase in the 7-day moving average of PM
was associated with a 1.20% (95% CI: 0.71, 1.71) increase in ALRI hospitalization. While we found similar estimates in a stratified analysis by sex, we observed stronger estimates of the association in the warm season (1.71%, 95% CI: 0.94, 2.48) compared to the cold season (0.31%, 95% CI: -0.51, 1.13). In the two-pollutant models, the PM
effect adjusted by SO
was attenuated more than in the single pollutant model. Our results suggest a positive association between PM
exposure and ALRI hospitalizations in Korean children, particularly in the warm season. The children need to refrain from going out on days when PM
is high. |
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Bibliography: | Contribute equally as first author. |
ISSN: | 1660-4601 1661-7827 1660-4601 |
DOI: | 10.3390/ijerph18010144 |