Presence of thrombophilia and levels of coagulation factors, coagulation inhibitors and TAFI do not affect global haemostasis or bleeding phenotype in patients with haemophilia A
•Proteins C and S explain part of OHP and ETP posttreatment values in haemophilia A.•Thrombophilia does not protect against a severe bleeding phenotype.•The prevalence of thrombophilia in haemophilia A patients is similar to controls.•OHP and ETP were not affected by coagulation factors and TAFI....
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Published in | Thrombosis research Vol. 173; pp. 1 - 3 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Ltd
01.01.2019
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Subjects | |
Online Access | Get full text |
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Summary: | •Proteins C and S explain part of OHP and ETP posttreatment values in haemophilia A.•Thrombophilia does not protect against a severe bleeding phenotype.•The prevalence of thrombophilia in haemophilia A patients is similar to controls.•OHP and ETP were not affected by coagulation factors and TAFI. |
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Bibliography: | SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 |
ISSN: | 0049-3848 1879-2472 1879-2472 |
DOI: | 10.1016/j.thromres.2018.11.008 |