Presence of thrombophilia and levels of coagulation factors, coagulation inhibitors and TAFI do not affect global haemostasis or bleeding phenotype in patients with haemophilia A

•Proteins C and S explain part of OHP and ETP posttreatment values in haemophilia A.•Thrombophilia does not protect against a severe bleeding phenotype.•The prevalence of thrombophilia in haemophilia A patients is similar to controls.•OHP and ETP were not affected by coagulation factors and TAFI....

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Published inThrombosis research Vol. 173; pp. 1 - 3
Main Authors Mikovic, Danijela, Pruner, Iva, Antovic, Jovan P., Chaireti, Roza
Format Journal Article
LanguageEnglish
Published United States Elsevier Ltd 01.01.2019
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Summary:•Proteins C and S explain part of OHP and ETP posttreatment values in haemophilia A.•Thrombophilia does not protect against a severe bleeding phenotype.•The prevalence of thrombophilia in haemophilia A patients is similar to controls.•OHP and ETP were not affected by coagulation factors and TAFI.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:0049-3848
1879-2472
1879-2472
DOI:10.1016/j.thromres.2018.11.008