Liver and small bowel transplantation: therapeutic alternatives for the treatment of liver disease and intestinal failure

Intestinal transplantation is an established life-saving therapy for parenteral nutrition dependent patients suffering from severe complications of parenteral nutrition. Improvements in outcomes over the last decade have occurred with refinements in surgical technique, better immunosuppressive regim...

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Bibliographic Details
Published inSeminars in liver disease Vol. 20; no. 4; p. 437
Main Authors Gilroy, R, Sudan, D
Format Journal Article
LanguageEnglish
Published United States 2000
Subjects
Humans
Intestinal Diseases - therapy
Intestine, Small - transplantation
Liver Failure - therapy
Liver Transplantation - adverse effects
Liver Transplantation - methods
Morbidity
Parenteral Nutrition - adverse effects
Patient Selection
Postoperative Care
Short Bowel Syndrome - therapy
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Summary:Intestinal transplantation is an established life-saving therapy for parenteral nutrition dependent patients suffering from severe complications of parenteral nutrition. Improvements in outcomes over the last decade have occurred with refinements in surgical technique, better immunosuppressive regimens, and clinical experience. The long-term results of intestinal transplantation are not well known and morbidity remains an important obstacle to wider application of this procedure to patients with short bowel syndrome (SBS). This article reviews the indications for intestinal transplantation, the evaluation of potential candidates, therapeutic considerations, postoperative management and common complications experienced by the recipients.
ISSN:0272-8087
1098-8971
DOI:10.1055/s-2000-13151