Metabolism of chlorsulfuron by tolerant broadleaves

• Published in: Pesticide biochemistry and physiology Vol. 22; no. 2; pp. 243 - 247
• Main Authors: Hutchison, J.M., Shapiro, R., Sweetser, P.B.
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 01.10.1984; Elsevier
• Subjects: ARBOLES FORESTALES; ARBRE FORESTIER; Biological and medical sciences; FLAX; FOREST TREES; Fundamental and applied biological sciences. Psychology; GRAMINEAS; GRAMINEE; GRASSES; HERBICIDAS; HERBICIDE; HERBICIDES; LIN; LINO; LINUM USITATISSIMUM; METABOLISM; METABOLISME; METABOLISMO; Parasitic plants. Weeds; Phytopathology. Animal pests. Plant and forest protection; Plant viruses and viroids; SOLANUM; SOLANUM NIGRUM; Systematics. Structure, properties and multiplication. Genetics; Linum usitatissimum; Solanum nigrum; Linaceae; Weed; Dicotyledones; Angiospermae; Tolerance; Spermatophyta; Solanaceae; Metabolism; Fiber crop; Herbicide
• ISSN: 0048-3575; 1095-9939
• DOI: 10.1016/0048-3575(84)90095-6

The ability of flax and black nightshade to metabolize chlorsulfuron was studied to determine if metabolism contributes to tolerance and to identify any metabolites produced. Plant leaves were treated with [ 14C]chlorsulfuron for a 24-hr period. The metabolites were extracted, separated by HPLC, and characterized. Mass spectral analysis and independent synthesis confirmed a major metabolite (B-1) as 2-chloro- N-{[4-(hydroxymethyl)-6-methoxy-1,3,5-triazin-2-yl]amino-carbonyl}benzenesulfonamide. A second major metabolite (B) was determined to be a carbohydrate conjugate of B-1. Plants were more tolerant to B-1 applications than to chlorsulfuron. These results suggest that metabolism may be the basis of selectivity to chlorsulfuron for tolerant broadleaf plants as well as for grasses.