Treatment of caffeine toxicity with esmolol

We present the case of a 58-year-old woman who ingested more than 35 g of caffeine in a suicide attempt. She manifested all the clinical symptoms and signs of caffeine toxicity. Esmolol, an ultrashort-acting β1-selective antagonist, controlled her multiple dysrhythmias and symptoms of sympathetic ne...

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Bibliographic Details
Published inAnnals of emergency medicine Vol. 19; no. 1; pp. 44 - 46
Main Authors Price, Kathleen Ray, Fligner, Denise J
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.01.1990
Elsevier
Subjects
Adrenergic beta-Antagonists - therapeutic use
Biological and medical sciences
Caffeine - poisoning
caffeine toxicity
Cardiac Complexes, Premature - chemically induced
Cardiac Complexes, Premature - drug therapy
Female
Food toxicology
Humans
Infusions, Intravenous
Medical sciences
Middle Aged
Propanolamines - administration & dosage
Propanolamines - therapeutic use
Suicide, Attempted
Tachycardia, Supraventricular - chemically induced
Tachycardia, Supraventricular - drug therapy
Toxicology
caffeine toxicity
Human
Electrodiagnosis
Chemotherapy
Treatment
Electrocardiography
Poisoning
Resuscitation
Beta blocking agent
Caffeine
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Summary:We present the case of a 58-year-old woman who ingested more than 35 g of caffeine in a suicide attempt. She manifested all the clinical symptoms and signs of caffeine toxicity. Esmolol, an ultrashort-acting β1-selective antagonist, controlled her multiple dysrhythmias and symptoms of sympathetic nervous system hyperstimulation. We suggest the use of esmolol for treatment of dysrhythmias secondary to caffeine toxicity; to the best of our knowledge, the use of esmolol has not been reported for this purpose.
ISSN:0196-0644
1097-6760
DOI:10.1016/S0196-0644(05)82139-0