Evaluation of a high-density oligonucleotide array for characterization of grlA, grlB, gyrA and gyrB mutations in fluoroquinolone resistant Staphylococcus aureus isolates
Using high-density oligonucleotide array technology, 30 Staphylococcus aureus strains were studied for the presence of mutations in genes involved in fluoroquinolone resistance: grlA, gyrA, grlB and gyrB. For the two most important genes, gyrA and grlA, correlation with sequencing reached 95.1%. If...
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Published in | Journal of microbiological methods Vol. 60; no. 2; pp. 275 - 279 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Shannon
Elsevier B.V
01.02.2005
Elsevier Science |
Subjects | |
Online Access | Get full text |
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Summary: | Using high-density oligonucleotide array technology, 30
Staphylococcus aureus strains were studied for the presence of mutations in genes involved in fluoroquinolone resistance:
grlA,
gyrA,
grlB and
gyrB. For the two most important genes,
gyrA and
grlA, correlation with sequencing reached 95.1%. If all genes were considered, correlation was 88.8%. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0167-7012 1872-8359 |
DOI: | 10.1016/j.mimet.2004.09.015 |