Estimated Costs Associated with Surgical Site Infections in Patients Undergoing Cholecystectomy

• Published in: International journal of environmental research and public health Vol. 19; no. 2; p. 764
• Main Authors: Algado-Sellés, Natividad, Mira-Bernabeu, Javier, Gras-Valentí, Paula, Chico-Sánchez, Pablo, Jiménez-Sepúlveda, Natali Juliet, Fuster-Pérez, Marina, Sánchez-Payá, José, Ronda-Pérez, Elena María
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.01.2022; MDPI
• Subjects: Antibiotics; Cholecystectomy; Control programs; Costs; Disease prevention; Economic impact; Epidemiology; Health care expenditures; Hospital costs; Humans; Infection Control; Infections; Intervention; Laparoscopy; Length of Stay; Multivariate analysis; Nosocomial infections; Patients; Preventive medicine; Prolongation; Prospective Studies; Regression analysis; Risk analysis; Risk factors; Surgery; Surgical site infections; Surgical Wound Infection - epidemiology; Systemic diseases; Variables; cholecystectomy; cost analysis; healthcare costs; surgical wound infection; healthcare-associated infections
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph19020764

Among healthcare-associated infections, surgical site infections (SSIs) are the most frequent in Spain. The aim of this work was to estimate the costs of SSIs in patients who underwent a cholecystectomy at the Hospital General Universitario de Alicante (Spain) between 2012-2017. This was a prospective observational cohort study. The Active Epidemiological Surveillance Program at our hospital recorded all the cholecystectomies performed. Risk factors associated with the development of SSIs were determined by multivariate analysis and two homogeneous comparison groups were obtained by using the propensity score. The number of extra days of hospital stay were recorded for patients with an SSI and with the cost per hospitalised day data, the additional cost attributed to SSIs was calculated. A total of 2200 cholecystectomies were considered; 110 patients (5.0%) developed an SSI. The average length of hospital stay was 5.6 days longer among patients with an SSI. The cost per SSI was EUR 1890.60 per patient, with the total cost for this period being EUR 207,961.60. SSIs after cholecystectomy lead to a prolongation of hospital stay and an increase in economic costs. It is essential to implement infection surveillance and control programs to reduce SSIs, improve patient safety, and reduce economic burden.