Point-of-care diagnostics, a major opportunity for change in traditional diagnostic approaches: potential and limitations

'Point-of-care' (POC) diagnostics are a powerful emerging healthcare approach. They can rapidly provide statistically significant results, are simple to use, do not require specialized equipment and are cost-effective. For these reasons, they have the potential to play a major role in revo...

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Bibliographic Details
Published inExpert review of molecular diagnostics Vol. 14; no. 8; p. 979
Main Authors McPartlin, Daniel A, O'Kennedy, Richard J
Format Journal Article
LanguageEnglish
Published England 01.11.2014
Subjects
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Biosensing Techniques - standards
Cardiovascular Diseases - diagnosis
Diagnostic Techniques and Procedures
HIV Infections - diagnosis
Humans
Neoplasms - diagnosis
Point-of-Care Systems - standards
Tuberculosis - diagnosis
cardiovascular disease
prostate cancer
antibody
biosensor
HIV
POC
mHealth
TB
acute myocardial infarction
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Summary:'Point-of-care' (POC) diagnostics are a powerful emerging healthcare approach. They can rapidly provide statistically significant results, are simple to use, do not require specialized equipment and are cost-effective. For these reasons, they have the potential to play a major role in revolutionizing the diagnosis, initiation and monitoring of treatment of major global diseases. This review focuses on antibody-based POC devices that target four major global diseases: cardiovascular diseases, prostate cancer, HIV infection and tuberculosis. The key statistics and pathology of each disease is described in detail, followed by an in-depth discussion on emerging POC devices that target each disease, highlighting their potential and limitations.
ISSN:1744-8352
DOI:10.1586/14737159.2014.960516