The role of platelet-activating factor in inflammation
An increasing body of evidence supports the hypothesis that platelet-activating factor (PAF) plays a major role in the physiopathology of inflammatory reactions. Much of this knowledge derives from studies that have identified and characterized different biological activities of PAF by using pharmac...
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Published in | Clinical Immunology and Immunopathology Vol. 57; no. 3; pp. 331 - 338 |
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Main Authors | , , |
Format | Book Review Journal Article |
Language | English |
Published |
San Diego, CA
Elsevier Inc
01.12.1990
New York, NY Academic Press Boston |
Subjects | |
Online Access | Get full text |
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Summary: | An increasing body of evidence supports the hypothesis that platelet-activating factor (PAF) plays a major role in the physiopathology of inflammatory reactions. Much of this knowledge derives from studies that have identified and characterized different biological activities of PAF by using pharmacological rather than physiological concentrations of this phospholipid. Therefore, PAF activities have been mainly identified with potentially detrimental rather than physiological effects. However, it is still surprising how this simple phospholipid exerts such striking effects. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0090-1229 1090-2341 |
DOI: | 10.1016/0090-1229(90)90108-3 |