SAPHO syndrome with temporomandibular joint ankylosis: clinical, radiological, histopathological, and therapeutical correlations

• Published in: Oral surgery, oral medicine, oral pathology, oral radiology and endodontics Vol. 105; no. 3; pp. e67 - e72
• Main Authors: Utumi, Estevam Rubens, DDS, Oliveira Sales, Marcelo Augusto, DDS, MSc, PhD, Shinohara, Elio Hitoshi, DDS, MSc, PhD, Takahashi, André, DDS, MSc, Coracin, Fábio Luiz, DDS, MSc, Rocha, Rodney Garcia, DDS, MSc, PhD, Paraíso Cavalcanti, Marcelo Gusmão, DDS, MSc, PhD
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01.03.2008
• Subjects: Acquired Hyperostosis Syndrome - complications; Acquired Hyperostosis Syndrome - diagnostic imaging; Adult; Ankylosis - complications; Ankylosis - diagnostic imaging; Dentistry; Humans; Male; Radiography, Panoramic; Range of Motion, Articular; Surgery; Temporomandibular Joint Disorders - complications; Temporomandibular Joint Disorders - diagnostic imaging
• ISSN: 1079-2104; 1528-395X
• DOI: 10.1016/j.tripleo.2007.09.010

The SAPHO syndrome is characterized by specific clinical manifestations of synovitis, acne pustulosis, hyperostosis, and osteitis. It is a rare disease with a combination of osseous and articular manifestations associated with skin lesions. We describe a patient with SAPHO syndrome of the mandible and involvement of the temporomandibular joint (TMJ ankylosis). The findings from orthopantomography, computed tomography (CT), and clinical and histopathological examinations are compared and analyzed to improve the final diagnosis. Our patient was submitted to a bilateral high condylectomy and coronoidectomy to correct the open mouth limitation. No previous report of SAPHO syndrome associated with secondary TMJ ankylosis was found in the literature.