The yield of continuous EEG monitoring in the intensive care unit at a tertiary care hospital in Saudi Arabia: A retrospective study [version 3; peer review: 2 approved, 1 approved with reservations]

• Published in: F1000 research Vol. 8; p. 663
• Main Author: Tayeb, Haythum O
• Format: Journal Article
• Language: English
• Published: London Faculty of 1000 Ltd 01.01.2019; F1000 Research Limited; F1000 Research Ltd
• Subjects: Brain research; Convulsions & seizures; EEG; Electroencephalography; Epilepsy; Hospitals; Intensive care; Morbidity; Mortality; Patients; Physicians; Rhythms; Seizures; Standard deviation; Statistical analysis; Studies; Traumatic brain injury; Saudi Arabia; North America; Europe; Saudi Arabia; status epilepticus; Neurocritical care; EEG; non-convulsive seizures
• ISSN: 2046-1402; 2046-1402
• DOI: 10.12688/f1000research.19237.3

Background: The practice of continuous EEG monitoring (CEEG) in the intensive care unit (ICU) has spread over the past decade. Building an effective ICU CEEG program demands adequate EEG equipment and human resources. This may not be available in developing healthcare systems. This study sought to shed light on the real-life utility of CEEG at a tertiary healthcare center in the developing healthcare system of Saudi Arabia. Methods: This is a retrospective review of CEEG findings, along with mortality and duration of hospitalization of patients who had CEEG during a 12-month period at the adult ICU at the King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia. Results: A total of 202 CEEG records were identified. A total of 52 records showed non-convulsive seizures (NCS); 10 clearly fulfilled criteria for non-convulsive status epilepticus. There were 120 patients that had clinical seizures upon presentation. Among them, 36 (30%) had NCS on EEG. The proportion of patients who were deceased at 60 days was higher in patients with NCS than those who didn't have NCS (42% vs 27%, χ 2 = 4.4, df=2, p=0.03). There was no statistically significant association between having rhythmic or periodic patterns without NCS and mortality at 60 days or length of hospital stay. Conclusion: This retrospective study demonstrates a real-world experience from a tertiary care center in Saudi Arabia, a developing healthcare system. ICU CEEG was found to be effective in detecting potentially harmful subclinical patterns, supporting the need to develop ICU CEEG programs. However, the incurred excesses in morbidity and mortality associated with CEEG patterns were relatively modest. Further studies are needed to delineate how the practice of CEEG may be developed in similar healthcare systems to provide meaningful data to clinicians with regards to patient outcomes.