Demographic characteristics and risk factors for invasive fungal sinusitis in the context of COVID-19: A systematic review and meta-analysis
•Invasive fungal sinusitis patients with COVID-19 had an average age of 53.72 years.•Invasive fungal sinusitis patients with COVID-19 were predominantly males.•The mean onset interval from COVID-19 to Invasive fungal sinusitis was 19.09 days.•The most common comorbidity among invasive fungal sinusit...
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Published in | International journal of infectious diseases Vol. 144; p. 107054 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Canada
Elsevier Ltd
01.07.2024
Elsevier |
Subjects | |
Online Access | Get full text |
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Summary: | •Invasive fungal sinusitis patients with COVID-19 had an average age of 53.72 years.•Invasive fungal sinusitis patients with COVID-19 were predominantly males.•The mean onset interval from COVID-19 to Invasive fungal sinusitis was 19.09 days.•The most common comorbidity among invasive fungal sinusitis patients was diabetes.•Diabetes, steroid administration, and COVID-19 PCR positivity were risk factors.
To identify the demographic characteristics and potential risk factors of invasive fungal sinusitis (IFS) patients with Coronavirus Disease in 2019 (COVID-19).
Web of Science, Embase, the Cochrane Library, and PubMed were searched from database inception to August 2023 using the combination of medical searching heading terms “invasive fungal sinusitis” and “COVID-19” and their free words. The research protocol was registered on PROSPERO (CRD42023467175).
A total of 53 studies were included. The mean age of IFS patients with COVID-19 was 53.72 (95% credible interval [CI]: 51.08, 56.36), with 66% males (95% CI: 0.62, 0.70), and 81% diabetes (95% CI: 0.77, 0.86). The mean time from COVID-19 diagnosis to IFS onset was 19.09 days (95% CI: 16.96, 21.22). The percentage of patients with COVID-19 PCR positivity was 33% (95% CI: 0.21, 0.45). Overall, 71% of patients receiving steroid therapy during COVID-19 infection (95% CI: 0.63, 0.78). The odds ratio of diabetes mellitus, steroid administration, and COVID-19 PCR positivity were 6.09, 2.21, and 1.82, respectively. COVID-19 infection did not affect the IFS stage.
IFS patients with COVID-19 had an average age of 53.72 years and were predominantly males, with a mean interval of 19.09 days from COVID-19 diagnosis to IFS onset. Diabetes, steroid administration, and COVID-19 PCR positivity were risk factors. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
ISSN: | 1201-9712 1878-3511 1878-3511 |
DOI: | 10.1016/j.ijid.2024.107054 |