Can single pulse electrical stimulation provoke responses similar to spontaneous interictal epileptiform discharges?

Highlights • Patients have several spontaneous interictal epileptiform discharge (IED) patterns and the areas showing IEDs are more widespread and multifocal than the area of seizure onset zone. • Delayed responses to single pulse electrical stimulation (SPES) are always similar to at least one IED...

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Bibliographic Details
Published inClinical neurophysiology Vol. 125; no. 7; pp. 1306 - 1311
Main Authors Nayak, Dinesh, Valentín, Antonio, Selway, Richard P, Alarcón, Gonzalo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ireland Ltd 01.07.2014
Subjects
Adolescent
Adult
Brain Mapping
Electric Stimulation
Electrodes - classification
Electroencephalography
Epilepsy surgery
Female
Heart Rate
Humans
Male
Middle Aged
Neurology
Seizure onset
Seizures - diagnosis
Seizures - physiopathology
Single pulse electrical stimulation
SPES – interictal epileptiform discharge
Young Adult
Seizure onset
Epilepsy surgery
Single pulse electrical stimulation
SPES – interictal epileptiform discharge
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Summary:Highlights • Patients have several spontaneous interictal epileptiform discharge (IED) patterns and the areas showing IEDs are more widespread and multifocal than the area of seizure onset zone. • Delayed responses to single pulse electrical stimulation (SPES) are always similar to at least one IED pattern in the same patient and occur at or in the vicinity of the seizure onset zone. • IEDs and SPES responses may share similar physiological mechanisms and the IEDs resembling delayed responses to SPES may be those IEDs associated with seizure onset.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2013.11.019