Axonal transport of neuroreceptors: possible involvement in long-term memory

Evidence is presented that neuroreceptors move bidirectionally along axons of neurons through fast axoplasmic transport mechanisms. The retrograde transport of receptor-bound signal molecules from nerve terminals to the perikaryon represents a corridor of information between synapses and the cell bo...

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Bibliographic Details
Published inNeuroscience Vol. 22; no. 3; p. 767
Main Author Laduron, P M
Format Journal Article
LanguageEnglish
Published United States 01.09.1987
Subjects
Animals
Axonal Transport
Memory - physiology
Receptors, Cell Surface - metabolism
Receptors, Cell Surface - physiology
Receptors, Nerve Growth Factor
Receptors, Neurotransmitter - metabolism
Receptors, Neurotransmitter - physiology
Receptors, Opioid - metabolism
Receptors, Opioid - physiology
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Summary:Evidence is presented that neuroreceptors move bidirectionally along axons of neurons through fast axoplasmic transport mechanisms. The retrograde transport of receptor-bound signal molecules from nerve terminals to the perikaryon represents a corridor of information between synapses and the cell body of neurons. It is speculated that this process could be involved in long-term memory.
ISSN:0306-4522
DOI:10.1016/0306-4522(87)92958-7