Immune-Mediated Diseases from the Point of View of Psychoneuroimmunoendocrinology

• Published in: Biology (Basel, Switzerland) Vol. 11; no. 7; p. 973
• Main Authors: Ortega, Miguel A, García-Montero, Cielo, Fraile-Martinez, Oscar, Alvarez-Mon, Miguel Angel, Gómez-Lahoz, Ana Maria, Lahera, Guillermo, Monserrat, Jorge, Rodriguez-Jimenez, Roberto, Quintero, Javier, Álvarez-Mon, Melchor
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.06.2022; MDPI
• Subjects: Arthritis; Chronic illnesses; Cytokines; Cytotoxicity; Diabetes; Disease; Endocrine system; Health care; Immune system; immune-mediated inflammatory diseases (IMID); Immunology; Inflammatory bowel disease; Inflammatory bowel diseases; integrative medicine; Metabolism; Nervous system; Patients; Physiology; Psoriasis; Psychologists; psychoneuroimmunoendocrinology (PNIE); psychosomatic therapy; Quality of life; Review; Rheumatoid arthritis; Ulcerative colitis; United States > US; Europe; psychosomatic therapy; integrative medicine; immune-mediated inflammatory diseases (IMID); psychoneuroimmunoendocrinology (PNIE)
• ISSN: 2079-7737; 2079-7737
• DOI: 10.3390/biology11070973

Immune-mediated inflammatory diseases (IMIDs) represent a large group of diseases (Crohn's, ulcerative colitis, psoriasis, lupus, and rheumatoid arthritis) evidenced by systemic inflammation and multiorgan involvement. IMIDs result in a reduced quality of life and an economic burden for individuals, health care systems, and countries. In this brief descriptive review, we will focus on some of the common biological pathways of these diseases from the point of view of psychoneuroimmunoendocrinology (PNIE). PNIE consists of four medical disciplines (psychology, nervous system, immune system, and endocrine system), which are key drivers behind the health-disease concept that a human being functions as a unit. We examine these drivers and emphasize the need for integrative treatments that addresses the disease from a psychosomatic point of view.