A study of peritoneal metastatic xenograft model of colorectal cancer in the treatment of hyperthermic intraperitoneal chemotherapy with Raltitrexed

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Bibliographic Details
Published inBiomedicine & pharmacotherapy Vol. 92; pp. 149 - 156
Main Authors Qiu, Cen, Li, Yueqi, Liang, Xin, Qi, Yingxue, Chen, Yiyang, Meng, Xianke, Zheng, Hongtu, Xu, Ye, Cai, Sanjun, Cai, Guoxiang, Liu, Jianwen
Format Journal Article
LanguageEnglish
Published France Elsevier Masson SAS 01.08.2017
Subjects
Absorption, Physiological
Animals
Antimetabolites, Antineoplastic - administration & dosage
Antimetabolites, Antineoplastic - adverse effects
Antimetabolites, Antineoplastic - pharmacokinetics
Antimetabolites, Antineoplastic - therapeutic use
Apoptosis - drug effects
Carcinoma - drug therapy
Carcinoma - pathology
Carcinoma - secondary
Carcinoma - therapy
Colorectal cancer
Colorectal Neoplasms - drug therapy
Colorectal Neoplasms - metabolism
Colorectal Neoplasms - pathology
Colorectal Neoplasms - therapy
Combined Modality Therapy - adverse effects
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Female
Half-Life
Hot Temperature
Humans
Hyperthermia, Induced - adverse effects
Hypertherrmic intraperitoneal perfusion
Infusions, Parenteral
Internal Medicine
Male
Medical Education
Mice, Nude
Peritoneal metastasis xenograft
Peritoneal Neoplasms - drug therapy
Peritoneal Neoplasms - pathology
Peritoneal Neoplasms - secondary
Peritoneal Neoplasms - therapy
Pharmacodynamics
Pharmacokinetics
Quinazolines - administration & dosage
Quinazolines - adverse effects
Quinazolines - pharmacokinetics
Quinazolines - therapeutic use
Raltitrexed
Random Allocation
Thiophenes - administration & dosage
Thiophenes - adverse effects
Thiophenes - pharmacokinetics
Thiophenes - therapeutic use
Tumor Burden
Xenograft Model Antitumor Assays
Raltitrexed
Pharmacodynamics
Hypertherrmic intraperitoneal perfusion
Pharmacokinetics
Peritoneal metastasis xenograft
Colorectal cancer
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Summary:Graphical abstract
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0753-3322
1950-6007
DOI:10.1016/j.biopha.2017.04.053