Surgical therapy for 101 patients with acquired immunodeficiency syndrome and symptomatic cholecystitis

• Published in: The American journal of surgery Vol. 174; no. 4; pp. 414 - 416
• Main Authors: Leiva, Jorge I., Etter, E. Leon, Gathe, Joseph, Bonefas, Elizabeth T., Melartin, Rick, Gathe, Joseph C.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.10.1997; Elsevier; Elsevier Limited
• Subjects: Acquired immune deficiency syndrome; Acquired Immunodeficiency Syndrome - complications; AIDS; AIDS-Related Opportunistic Infections - surgery; AIDS/HIV; Biological and medical sciences; Calculi; Cholecystectomy; Cholecystectomy, Laparoscopic; Cholecystitis; Cholecystitis - complications; Cholecystitis - surgery; Cholelithiasis - complications; Cholelithiasis - surgery; Cryptosporidium; Cytomegalovirus; Female; Gallbladder; Gallbladder diseases; Humans; Immune system; Immunodeficiency; Laparoscopy; Liver, biliary tract, pancreas, portal circulation, spleen; Male; Malignancy; Medical sciences; Medical treatment; Morbidity; Mortality; Pathogens; Quality of life; Retrospective Studies; Signs and symptoms; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Treatment Outcome; Cholecystectomy; Human; Immunopathology; Prognosis; Mortality; AIDS; Biliary tract disease; Immune deficiency; Morbidity; Infection; Treatment; Surgery; Viral disease; Digestive diseases; Complication; Gallbladder; Cholecystitis
• ISSN: 0002-9610; 1879-1883
• DOI: 10.1016/S0002-9610(97)00118-9

Hepatobiliary disease in patients with acquired immunodeficiency syndrome (AIDS) has been well documented. Cytomegalovirus and Cryptosporidium are the pathogens most frequently associated. Previous reports of cholecystectomies and AIDS have had conflicting results on morbidity and mortality. Retrospective review of 101 patients with AIDS and symptomatic cholecystitis who underwent cholecystectomy from December 1989 to May 1995. All patients had symptoms characteristic of gallbladder disease, the most common being abdominal pain and fever. Thickening of the gallbladder was the most common diagnostic finding. Fifty-six patients underwent open cholecystectomy and 45 laparoscopic cholecystectomy. Pathologic examination revealed an abnormal gallbladder in all cases and gallstones in 29%. A specific pathogen or malignancy was identified as the etiologic agent in 44% of patients. Perioperative morbidity was similar (<5%) in both surgical groups. Perioperative mortality was 4% among all the patients treated. Both open and laparoscopic cholecystectomy improved the quality of life of these patients and should be considered as the treatment for persistent hepatobiliary symptoms in patients with AIDS.