Ten-year outcome after coronary angioplasty in patients with single-vessel coronary artery disease and comparison with the results of the Coronary Artery Surgery Study (CASS)

• Published in: The American journal of cardiology Vol. 85; no. 3; pp. 321 - 326
• Main Authors: Espinola-Klein, Christine, Rupprecht, Hans-Jürgen, Erbel, Raimund, Nafe, Bernhard, Brennecke, Rüdiger, Meyer, Jürgen
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.2000; Elsevier; Elsevier Limited
• Subjects: Adrenergic beta-Antagonists - therapeutic use; Angioplasty; Angioplasty, Balloon, Coronary - mortality; Anticoagulants - therapeutic use; Biological and medical sciences; Calcium Channel Blockers - therapeutic use; Cardiology; Cardiovascular disease; Clinical outcomes; Coronary Artery Bypass - mortality; Coronary Disease - drug therapy; Coronary Disease - therapy; Disease-Free Survival; Diseases of the cardiovascular system; Female; Follow-Up Studies; Germany - epidemiology; Humans; Hypolipidemic Agents - therapeutic use; Male; Medical sciences; Middle Aged; Nitroglycerin - therapeutic use; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Surveys and Questionnaires; Survival Analysis; Treatment Outcome; Germany; Human; Drug; Prognosis; Mortality; Coronary artery; Instrumentation therapy; Cuffed tube; Cardiovascular disease; Instrumental dilatation; Coronary heart disease; Long term; Morbidity; Five year survival; Chemotherapy; Treatment; Aortocoronary; Bypass; Surgery; Evolution; Graft; Comparative study
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/S0002-9149(99)00740-7

The 10-year results of randomized trials comparing percutaneous transluminal coronary angioplasty (PTCA) in patients with single-vessel coronary artery disease (CAD) with coronary artery bypass grafting (CABG) and medical treatment are not available yet. The aim of this evaluation was to compare our 10-year follow-up results after PTCA in patients with single-vessel CAD with the 10-year follow-up results after CABG and medical treatment in the Coronary Artery Surgery Study (CASS) trial. We evaluated the clinical outcome of 509 patients with single-vessel CAD 10 years after coronary angioplasty. The data were compared with the results of 214 patients with single-vessel CAD after CABG or medical treatment from the CASS trial. End points were defined as death and myocardial infarction. Statistical evaluation was performed by life-table analysis and 2-sided Fisher’s exact test. The rate of survival was 86% 10 years after PTCA compared with 85% after CABG and 82% after medical treatment in patients from the CASS trial (p = NS). Survival free from myocardial infarction was 77% after coronary angioplasty, 70% after CABG, and 72% after medical treatment (p = NS). Thus, in patients with single-vessel CAD, infarct-free survival 10 years after coronary angioplasty compared favorably with the results after bypass surgery or medical treatment from the CASS trial.