Origin of Replication of Mycoplasma genitalium
The complete sequence of the genome of Mycoplasma genitalium was reported and analyzed by Claire M. Fraser et al. (1). The origin of replication of the chromosome was not localized precisely because of the lack of consensus patterns, "DnaA boxes," in this species, but it was suggested that...
Saved in:
Published in | Science (American Association for the Advancement of Science) Vol. 272; no. 5262; pp. 745 - 746 |
---|---|
Main Author | |
Format | Journal Article |
Language | English |
Published |
Washington, DC
American Society for the Advancement of Science
03.05.1996
American Association for the Advancement of Science American Association for the Advancement of Science (AAAS) |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The complete sequence of the genome of Mycoplasma genitalium was reported and analyzed by Claire M. Fraser et al. (1). The origin of replication of the chromosome was not localized precisely because of the lack of consensus patterns, "DnaA boxes," in this species, but it was suggested that the origin might be in an untranscribed AT-rich region between dnaA and dnaN. This location can be confirmed using a new method based on the results of the mathematical analysis of the model of DNA evolution under no-strand-bias conditions (2) -- that is, when there is no strand-bias for the mutation process or for the selective process between the two strands of DNA. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Commentary-2 |
ISSN: | 0036-8075 1095-9203 |
DOI: | 10.1126/science.272.5262.745 |