Distinctive neuronal firing patterns in subterritories of the subthalamic nucleus

• Published in: Clinical neurophysiology Vol. 127; no. 11; pp. 3387 - 3393
• Main Authors: Pozzi, Nicolò G, Arnulfo, Gabriele, Canessa, Andrea, Steigerwald, Frank, Nickl, Robert, Homola, György A, Fato, Marco M, Matthies, Cordula, Pacchetti, Claudio, Volkmann, Jens, Isaias, Ioannis U
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2016
• Subjects: Action Potentials - physiology; Aged; Deep brain stimulation (STN); Deep Brain Stimulation - methods; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging - methods; Male; Micro-electrode recordings (MER); Middle Aged; Neurology; Neurons - physiology; Parkinson Disease - diagnosis; Parkinson Disease - physiopathology; Parkinson Disease - surgery; Parkinson’s disease (PD); Retrospective Studies; Subthalamic nucleus (STN); Subthalamic Nucleus - physiopathology; Subthalamic Nucleus - surgery; Tomography, X-Ray Computed - methods; Parkinson’s disease (PD); Deep Brain Stimulation (STN); Micro-electrode recordings (MER); Subthalamic Nucleus (STN); Deep brain stimulation (STN); Subthalamic nucleus (STN)
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2016.09.004

Highlights • We studied the neuronal activity of STN subterritories as anatomically defined on fused CT/MRI images. • We showed that STN subterritories exhibit a distinctive burst firing rate. • The different bursting activity might reflect the functional organisation of the STN.