The distribution and origin of axon terminals with NADPH diaphorase activity in the nucleus of the solitary tract of the rat

• Published in: Neuroscience letters Vol. 171; no. 1; pp. 70 - 72
• Main Authors: Lü, Yan, Ding, Yu-Qiang, Qin, Bing-Zhi, Li, Ji-Shuo
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 25.04.1994; Elsevier
• Subjects: Amino Acid Oxidoreductases - metabolism; Animals; Biochemistry and metabolism; Biological and medical sciences; Central nervous system; Female; Fundamental and applied biological sciences. Psychology; Ganglionectomy; Histocytochemistry; NADPH Dehydrogenase - metabolism; NADPH diaphorase; Neurons, Afferent - enzymology; Neurons, Afferent - physiology; Nitric Oxide Synthase; Nodose ganglion; Nodose Ganglion - physiology; Nucleus of the solitary tract; Presynaptic Terminals - enzymology; Presynaptic Terminals - physiology; Rat; Rats; Rats, Sprague-Dawley; Solitary Nucleus - cytology; Solitary Nucleus - enzymology; Vertebrates: nervous system and sense organs; Nucleus of the solitary tract; Nitric oxide synthase; NADPH diaphorase; Rat; Nodose ganglion; Enzyme; Rodentia; Central nervous system; NADPH dehydrogenase; Nitric-oxide synthase; Solitary nucleus; Vertebrata; Mammalia; Neuromediator; Nitrogen monoxide; Oxidoreductases; Histochemistry; Brain (vertebrata)
• ISSN: 0304-3940; 1872-7972
• DOI: 10.1016/0304-3940(94)90607-6

The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and caudal part of the NST. After removal of the nodose ganglion (NG), most of the axon terminals with NADPH activity in the NST were eliminated on the ipsilateral side. These results indicated that most of the axon terminals with NADPH diaphorase in the NST derive from the primary afferent neurons in the NG, and that NOS may be richly contained in the central terminals of NG neurons to produce nitric oxide as a transmitter.