The uptake of anionic and cationic amino acids by the isolated perfused sheep choroid plexus
The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier wit...
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| Published in | Brain research Vol. 581; no. 2; p. 351 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
29.05.1992
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| Subjects | |
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| Abstract | The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier with no cross-competition between them. In addition the uptake was markedly stereospecific with a high degree of selectivity and no interaction with the L-system amino acids. |
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| AbstractList | The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier with no cross-competition between them. In addition the uptake was markedly stereospecific with a high degree of selectivity and no interaction with the L-system amino acids. |
| Author | Preston, J E Segal, M B |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/1393540$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Animals Arginine - metabolism Aspartic Acid - metabolism Biological Transport - drug effects Choroid Plexus - metabolism Female Glutamates - metabolism Glutamates - pharmacology In Vitro Techniques Kinetics Lysine - metabolism Lysine - pharmacology Male Perfusion Sheep |
| Title | The uptake of anionic and cationic amino acids by the isolated perfused sheep choroid plexus |
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