Interactions of attapulgite (fibrous clay) with human red blood cells

The haemolytic potential of attapulgite (Senegal) has been investigated. When the particles were pretreated with dipalmitoyl phosphatidylcholine (DPPC) or with bovine serum albumin (BSA) at a concentration that would obtain maximum coverage of the particles by adsorption, a change in haemolysis was...

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Bibliographic Details
Published inToxicology letters Vol. 47; no. 3; p. 303
Main Authors Perderiset, M, Etienne, L S, Bignon, J, Jaurand, M C
Format Journal Article
LanguageEnglish
Published Netherlands 01.06.1989
Subjects
1,2-Dipalmitoylphosphatidylcholine - pharmacology
Hemolysis - drug effects
Humans
Kinetics
Magnesium - toxicity
Magnesium Compounds
Serum Albumin, Bovine - pharmacology
Silicon - toxicity
Silicon Compounds
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Summary:The haemolytic potential of attapulgite (Senegal) has been investigated. When the particles were pretreated with dipalmitoyl phosphatidylcholine (DPPC) or with bovine serum albumin (BSA) at a concentration that would obtain maximum coverage of the particles by adsorption, a change in haemolysis was observed. The results indicate that haemolysis is strongly dependent on the surface state of the particles.
ISSN:0378-4274
DOI:10.1016/0378-4274(89)90149-5