Opportunistic Community Screening of Chronic Chagas Disease Using a Rapid Diagnosis Test in Pharmacies in Barcelona (Catalonia, Spain): Study Protocol and Pilot Phase Results

• Published in: International journal of public health Vol. 67; p. 1605386
• Main Authors: Silgado, Aroa, Bosch-Nicolau, Pau, Sánchez-Montalvá, Adrián, Cervià, Ariadna, Gomez-I-Prat, Jordi, Bagaria, Guillermo, Rodriguez, Cristina, Goterris, Lidia, Serre-Delcor, Núria, Oliveira-Souto, Inés, Salvador, Fernando, Molina, Israel, Sulleiro, Elena
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.11.2022
• Subjects: Chagas disease; Chagas Disease - diagnosis; community pharmacies; dried blood; Hispanic or Latino; Humans; Mass Screening - methods; opportunistic screening; Pharmacies; Public Health Archive; rapid test; Spain; Spain; dried blood; Chagas disease; community pharmacies; opportunistic screening; rapid test
• ISSN: 1661-8564; 1661-8556; 1661-8564
• DOI: 10.3389/ijph.2022.1605386

This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed consent form, recording the patient's data in a web-based database system, and performing the rapid test and blood collection on dry paper. Nineteen pharmacies participated and 64 patients were included during the pilot phase of the study. The rapid diagnostic test (RDT) was positive in 2/64 (3.13%) cases. Of the 49 DBS samples that arrived at the laboratory, 22 (45%) were collected incorrectly. After quantitative and qualitative assessment of the program, the dry paper sample and passive strategy were ruled out. DBS sampling and the passive strategy are not suitable for CD screening in community pharmacies. There is a need to expand the number of participating pharmacies and individuals to determine whether conducting a RDT in community pharmacies is an effective screening method to increase access to CD diagnosis in a non-endemic area.