Schistosomal colitis without granuloma formation in a kidney transplant recipient

A 40-year-old male from the White Nile region in Sudan, who had received a kidney transplant 6 years previously, presented with fever, lower abdominal pain and diarrhea stained with blood of 5 months duration. He was on immunosuppressive maintenance therapy, consisting of ciclosporin 75 mg twice dai...

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Published inNature clinical practice. Gastroenterology & hepatology Vol. 3; no. 12; pp. 700 - 704
Main Authors Mudawi, Hatim MY, Elhassan, Elwaleed AM, Baraka, Omer Z, El Hassan, Ahmed M
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 01.12.2006
Subjects
Adult
Care and treatment
Case studies
Colitis
Diagnosis
Diagnosis, Differential
Dosage and administration
Health aspects
Humans
Immunocompromised Host
Kidney Transplantation
Male
Physiological aspects
Praziquantel
Schistosoma
Schistosomiasis mansoni - diagnosis
Schistosomiasis mansoni - drug therapy
Schistosomiasis mansoni - immunology
Sudan
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Summary:A 40-year-old male from the White Nile region in Sudan, who had received a kidney transplant 6 years previously, presented with fever, lower abdominal pain and diarrhea stained with blood of 5 months duration. He was on immunosuppressive maintenance therapy, consisting of ciclosporin 75 mg twice daily, prednisolone 10 mg once daily, and azathioprine 75 mg once daily. Laboratory investigations, liver function tests, renal function tests, stool microscopy, stool culture, abdominal ultrasound, and colonoscopy. Severe, left-sided colitis due to Schistosoma mansoni infection, without granuloma formation. Oral antischistosomal therapy with praziquantel at a dose of 40 mg/kg body weight.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:1743-4378
1759-5045
1743-4386
1759-5053
DOI:10.1038/ncpgasthep0655