Age-related changes of methionine-enkephalin and beta-endorphin/beta-lipotropin immunoreactivity in human CSF

Methionine-enkephalin (ME-IR) and beta-endorphin (BE-IR) immunoreactive material CSF concentrations have been measured in subjects of different ages affected by lumbar or cervical disk hernia. The two peptides exhibited different age-related trends. ME-IR levels rose significantly with age while no...

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Bibliographic Details
Published inLife sciences (1973) Vol. 43; no. 19; p. 1545
Main Authors Alessio, L, Govoni, S, Salar, G, Battaini, F, Iavicoli, R, Trabucchi, M
Format Journal Article
LanguageEnglish
Published Netherlands 1988
Subjects
Adult
Aged
Aging - cerebrospinal fluid
beta-Endorphin - cerebrospinal fluid
beta-Lipotropin - cerebrospinal fluid
Chromatography, High Pressure Liquid - methods
Enkephalin, Methionine - cerebrospinal fluid
Female
Humans
Male
Middle Aged
Radioimmunoassay - methods
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Summary:Methionine-enkephalin (ME-IR) and beta-endorphin (BE-IR) immunoreactive material CSF concentrations have been measured in subjects of different ages affected by lumbar or cervical disk hernia. The two peptides exhibited different age-related trends. ME-IR levels rose significantly with age while no changes were observed in the case of BE-IR.
ISSN:0024-3205
DOI:10.1016/0024-3205(88)90403-1