A rapid and sensitive micro-assay to determine the capacity of quinones to undergo redox cycling
Using a series of aziridinyl-benzoquinones it is shown that the conversion of oxyhemoglobin to methemoglobin in sheep erythrocytes is correlated with the capacity of each quinone to undergo redox cycling. Based on these findings a semiquantitative assay is developed for the rapid screening of redox...
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Published in | Toxicology letters Vol. 48; no. 2; p. 151 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
01.08.1989
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Subjects | |
Online Access | Get more information |
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Summary: | Using a series of aziridinyl-benzoquinones it is shown that the conversion of oxyhemoglobin to methemoglobin in sheep erythrocytes is correlated with the capacity of each quinone to undergo redox cycling. Based on these findings a semiquantitative assay is developed for the rapid screening of redox cycling quinones. |
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ISSN: | 0378-4274 |
DOI: | 10.1016/0378-4274(89)90169-0 |