Dysbiosis of gut microbiota and microbial metabolites in Parkinson’s Disease

• Published in: Ageing research reviews Vol. 45; pp. 53 - 61
• Main Authors: Sun, Meng-Fei, Shen, Yan-Qin
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.08.2018
• Subjects: Central nervous system; Gut microbiota; Microbial molecules; Microbiota-targeted therapies; Parkinson's disease; Short-chain fatty acids; Gut microbiota; Short-chain fatty acids; Microbiota-targeted therapies; Parkinson's disease; Microbial molecules; Central nervous system

•Gut microbial dysbiosis is found in patients with Parkinson’s disease (PD).•Microbial metabolites and microbial products contribute to PD pathology.•The microbiota-gut-brain axis plays a crucial role in PD.•Antibiotics, probiotics and FMT may be novel treatments for PD. Gut microbial dysbiosis and...