An epidemiology survey of vitamin D deficiency and its influencing factors

• Published in: Medicina clinica Vol. 154; no. 1; p. 7
• Main Authors: Jiang, Wei, Wu, Dong-Bo, Xiao, Gui-Bao, Ding, Bei, Chen, En-Qiang
• Format: Journal Article
• Language: English
• Published: Spain 10.01.2020
• Subjects: Adult; Age Factors; Aged; China - epidemiology; Cholecalciferol - blood; Cholecalciferol - deficiency; Cross-Sectional Studies; Female; Geography, Medical; Humans; Male; Middle Aged; Prevalence; Seasons; Sex Factors; Vitamin D - blood; Vitamin D Deficiency - blood; Vitamin D Deficiency - epidemiology; Young Adult; China; Factor de influencia; Vitamin D; Deficiency; Distribution; Adult population; Deficiencia; Distribución; Influencing factor; Población adulta; Vitamina D
• ISSN: 1578-8989
• DOI: 10.1016/j.medcli.2019.03.019

There is growing evidence that vitamin D is related to the development of a variety of diseases. The current study was performed to investigate the status of serum vitamin D distribution among adult Chinese people and reveal the influence of gender, age, seasonality and residential regions on serum vitamin D levels. This cross-sectional study included 14,302 participants aged from 18 years old to 65 years old from six major cities in China. The basic demographic information and the levels of serum vitamin D (25(OH)D) and vitamin D (25(OH)D ) were collected from Jan 2, 2014 to Dec 25, 2017. The prevalence of 25(OH)D concentration <30ng/mL reached up to 83%, in which the rate of vitamin D insufficiency (20-29ng/mL) was 32.7%, and vitamin D deficiency (10-19ng/mL) accounted for 41.9%, and vitamin D severe shortage (<10ng/mL) accounted for 8.4%. Women were more likely to have vitamin D deficiency and lower serum vitamin D concentration than men (both p<0.001). The mean concentration of serum 25(OH)D and 25(OH)D in summer and autumn were higher than that in spring and winter (p<0.001), and the mean concentration of serum 25(OH)D in people from Southern China was higher than that in people from other regions (p<0.001). Although the mean concentrations of serum 25(OH)D and 25(OH)D were both increased by age, the percentage of patients with serum 25(OH)D insufficiency was also increased. Serum vitamin D deficiency is very common in adults in China. The level of serum vitamin D may be associated with age, sex, seasonality and residential regions.