Phage phiC31 integrase: a new tool in plastid genome engineering

Plastid transformation offers the unique advantages of high-level transgene expression and increased transgene containment compared with conventional transgenic technologies. The process relies on the homologous recombination machinery of the plastid incorporating foreign DNA into the plastome, whic...

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Bibliographic Details
Published inTrends in plant science Vol. 10; no. 1; pp. 1 - 3
Main Authors Khan, Muhammad Sarwar, Khalid, Ahmad M., Malik, Kauser A.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 2005
Elsevier
Subjects
Bacteriophages - enzymology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Gene Expression
Genes. Genome
Genetic Engineering - methods
genetic recombination
integrase
Integrases - physiology
literature reviews
Molecular and cellular biology
Molecular genetics
Plants, Genetically Modified
plastids
Plastids - genetics
transgenic plants
viral proteins
Plastid
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Summary:Plastid transformation offers the unique advantages of high-level transgene expression and increased transgene containment compared with conventional transgenic technologies. The process relies on the homologous recombination machinery of the plastid incorporating foreign DNA into the plastome, which restricts the method to species where this type of incorporation works well. However, Pal Maliga and colleagues have recently reported a novel approach for integrating foreign DNA into the plastid genome that works independently of homologous recombination.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:1360-1385
1878-4372
DOI:10.1016/j.tplants.2004.11.001