Comparative Proteomic Analysis of Different Parts of Taenia Hydatigena

, a globally distributed parasite, is a canine tapeworm and causes huge economic losses in the food industry. Using LC-MS/MS, the proteomes of cyst scolex, designated as CS, and the cyst without the scolex, designated as CWS, were profiled and a total of 764 different proteins were identified, 664 o...

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Published inFrontiers in veterinary science Vol. 8; p. 626579
Main Authors Cai, Mengting, Li, Yating, He, Guitian, Guo, Xiaola, Zhang, Shaohua, Yan, Lujun, Zhang, Jing, Ding, Juntao
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 26.04.2021
Subjects
cestode
cyst
proteome
scolex
Taenia hydatigena
Veterinary Science
cestode
cyst
Taenia hydatigena
scolex
proteome
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Summary:, a globally distributed parasite, is a canine tapeworm and causes huge economic losses in the food industry. Using LC-MS/MS, the proteomes of cyst scolex, designated as CS, and the cyst without the scolex, designated as CWS, were profiled and a total of 764 different proteins were identified, 664 of which were identified in CS, 412 identified in CWS, and 312 in both. Comparative analysis revealed that CS had more abundant proteins associated with growth and development, while CWS had more abundant proteins constituting a scaffolding and protective extracellular matrix. Consistent with the sequencing data, the abundance of the five selected proteins was validated to be higher in CWS than CS by Western blotting. The current data will provide a clue for further pinpointing a role of these proteins in the biology of .
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Reviewed by: Xinyue Liu, Harvard Medical School, United States; Junzheng Du, Chinese Academy of Agricultural Sciences, China; Juan Pedro, Universidad Nacional Autónoma de México, Mexico
Edited by: Donato Traversa, University of Teramo, Italy
This article was submitted to Parasitology, a section of the journal Frontiers in Veterinary Science
These authors have contributed equally to this work
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2021.626579