Transient crossed aphasia evidenced by functional brain imagery

Crossed aphasia refers to language deficits induced by unilateral right hemisphere injuries in right-handed people who had no previous history of brain damage. One of the intriguing questions concerning crossed aphasia is the atypical language representation in the brain. In this respect, fMRI is a...

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Bibliographic Details
Published inNeuroreport Vol. 15; no. 5; p. 785
Main Authors Khateb, Asaid, Martory, Marie-Dominique, Annoni, Jean-Marie, Lazeyras, François, de Tribolet, Nicolas, Pegna, Alan J, Mayer, Eugène, Michel, Christoph M, Seghier, Mohamed L
Format Journal Article
LanguageEnglish
Published England 09.04.2004
Subjects
Aphasia - diagnosis
Aphasia - pathology
Brain Mapping
Brain Neoplasms - complications
Frontal Lobe - pathology
Functional Laterality - physiology
Humans
Language
Language Tests - statistics & numerical data
Magnetic Resonance Imaging - methods
Male
Meningioma - complications
Middle Aged
Neuropsychological Tests - statistics & numerical data
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Summary:Crossed aphasia refers to language deficits induced by unilateral right hemisphere injuries in right-handed people who had no previous history of brain damage. One of the intriguing questions concerning crossed aphasia is the atypical language representation in the brain. In this respect, fMRI is a valuable tool for understanding the neural basis of crossed aphasia. Here, we used neuropsychological and fMRI language tasks in a right-handed subject who presented a crossed aphasia due to a right frontal meningioma. fMRI maps from two language tasks showed bilateral patterns of activation. In the light of previous studies reporting much frequent bilateral than exclusive right hemisphere representations, we hypothesise that some crossed aphasia cases could occur in subjects with bilateral language representation.
ISSN:0959-4965
DOI:10.1097/00001756-200404090-00009