MR microscopy of cobalt-labeled nerve cells and pathways in an invertebrate brain (Sepia officinalis, Cephalopoda)
This article describes a novel application of contrast‐enhanced MR microscopy to trace nerve cells and pathways through small invertebrate brains. Using the cuttlefish Sepia officinalis (Cephalopoda) as a model, the cells and pathways of one of the brain nerves were labeled with paramagnetic cobalt(...
Saved in:
Published in | Magnetic resonance in medicine Vol. 45; no. 4; pp. 575 - 579 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
New York
John Wiley & Sons, Inc
01.04.2001
Williams & Wilkins |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | This article describes a novel application of contrast‐enhanced MR microscopy to trace nerve cells and pathways through small invertebrate brains. Using the cuttlefish Sepia officinalis (Cephalopoda) as a model, the cells and pathways of one of the brain nerves were labeled with paramagnetic cobalt(II) ions by conventional centripetal cobalt iontophoresis. In MR microscopy, the cobalt‐labeled cell bodies and pathways became hypointense in 9.4 T spin echo images. Their course and distribution were identical with those seen with conventional histological techniques after cobalt sulphide precipitation (with or without subsequent silver intensification). Magn Reson Med 45:575–579, 2001. © 2001 Wiley‐Liss, Inc. |
---|---|
Bibliography: | ArticleID:MRM1078 ark:/67375/WNG-FT30R7MZ-2 istex:2602A0691969AB1F27FF0BF8D265B841845BDAF1 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0740-3194 1522-2594 |
DOI: | 10.1002/mrm.1078 |