Adherence to study medication and visits: Data from the BABY HUG trial

• Published in: Pediatric blood & cancer Vol. 54; no. 2; pp. 260 - 264
• Main Authors: Thornburg, Courtney D., Rogers, Zora R., Jeng, Michael R., Rana, Sohail R., Iyer, Rathi V., Faughnan, Lane, Hassen, Leann, Marshall, Jennifer, McDonald, Roy P., Wang, Winfred C., Huang, Xiangke, Rees, Renée C.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.02.2010
• Subjects: Anemia, Sickle Cell - drug therapy; anti-sickling agents; Antisickling Agents - therapeutic use; clinical trial; Clinical Trials, Phase III as Topic; Female; Humans; Hydroxyurea - therapeutic use; Infant; Male; non-adherence; Patient Compliance; Patient Dropouts; Randomized Controlled Trials as Topic; study retention

Background Subject retention and adherence are essential to maintain the power and validity of the Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG). We designed a study to assess adherence with study medication administration and study visits and to evaluate socioeconomic factors (SES) that...